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2-Keto Crizotinib

Catalog No.: A21848

2-Keto Crizotinib

2-Keto Crizotinib Chemical Structure

CAS NO. 1415558-82-5

2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib.

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Biological Activity

2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.54 mL 107.68 mL 215.37 mL
0.5 mM 4.31 mL 21.54 mL 43.07 mL
1 mM 2.15 mL 10.77 mL 21.54 mL
5 mM 0.43 mL 2.15 mL 4.31 mL

*The above data is based on the productmolecular weight 464.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21848
CAS No. 1415558-82-5
Formula C21H20Cl2FN5O2
M. Wt 464.32
Purity >98%
Synonyms PF-06260182, PF 06260182, PF06260182
SMILES O=C1CC(N2N=CC(C3=CC(O[[email protected]](C)C4=C(Cl)C(F)=CC=C4Cl)=C(N)N=C3)=C2)CCN1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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