25-Hydroxycholesterol-d6 is a deuterium-labeled form of 25-Hydroxycholesterol, a metabolite of cholesterol synthesized and released by macrophages upon Toll-like receptor (TLR) activation. This compound serves as a selective and potent inhibitor of immunoglobulin A (IgA) production in B cells, with an effective concentration (EC50) of approximately 65 nM. Its unique labeling makes it a valuable tool for tracing cholesterol metabolism and studying immune response mechanisms in various research applications.
25-Hydroxycholesterol-d6 is a deuterium-labeled form of 25-Hydroxycholesterol, a metabolite of cholesterol synthesized and released by macrophages upon Toll-like receptor (TLR) activation. This compound serves as a selective and potent inhibitor of immunoglobulin A (IgA) production in B cells, with an effective concentration (EC50) of approximately 65 nM. Its unique labeling makes it a valuable tool for tracing cholesterol metabolism and studying immune response mechanisms in various research applications.
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