5,6-Epoxyeicosatrienoic acid-d11 is a deuterium-labeled analogue of 5,6-Epoxyeicosatrienoic acid (5,6-EET), a compound synthesized from arachidonic acid by cytochrome P450 enzymes. This stable isotope is valuable for studying the biological activities of 5,6-EET, which include modulation of calcium mobilization and hormone secretion in neuroendocrine cells, as well as inhibition of T-type voltage-gated calcium channels (Cav3.1, Cav3.2). Additionally, it functions as a substrate for COX-1 and COX-2, facilitating detailed metabolic studies. 5,6-Epoxyeicosatrienoic acid-d11 aids in quantification and mechanistic investigations through methods such as GC-MS.
5,6-Epoxyeicosatrienoic acid-d11 is a deuterium-labeled analogue of 5,6-Epoxyeicosatrienoic acid (5,6-EET), a compound synthesized from arachidonic acid by cytochrome P450 enzymes. This stable isotope is valuable for studying the biological activities of 5,6-EET, which include modulation of calcium mobilization and hormone secretion in neuroendocrine cells, as well as inhibition of T-type voltage-gated calcium channels (Cav3.1, Cav3.2). Additionally, it functions as a substrate for COX-1 and COX-2, facilitating detailed metabolic studies. 5,6-Epoxyeicosatrienoic acid-d11 aids in quantification and mechanistic investigations through methods such as GC-MS.
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