5-Hydroxy saxagliptin-13C,d2-2 hydrochloride is a stable isotope-labeled form of 5-Hydroxy saxagliptin hydrochloride, a potent and selective DPP-4 inhibitor. This active metabolite of Saxagliptin demonstrates Ki values of 2.6 nM in human enzymes and 2.9 nM in cynomolgus monkeys, highlighting its efficacy in inhibiting DPP-4 activity. It is valuable for research applications focusing on type 2 diabetes mellitus, enabling detailed metabolic studies and pharmacokinetic assessments.
5-Hydroxy saxagliptin-13C,d2-2 hydrochloride is a stable isotope-labeled form of 5-Hydroxy saxagliptin hydrochloride, a potent and selective DPP-4 inhibitor. This active metabolite of Saxagliptin demonstrates Ki values of 2.6 nM in human enzymes and 2.9 nM in cynomolgus monkeys, highlighting its efficacy in inhibiting DPP-4 activity. It is valuable for research applications focusing on type 2 diabetes mellitus, enabling detailed metabolic studies and pharmacokinetic assessments.
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