7-O-Galloyl-D-sedoheptulose is a polyphenolic compound recognized for its antioxidant, anti-inflammatory, and anti-fibrotic properties. It lowers serum levels of glucose, leptin, insulin, and pro-inflammatory cytokines such as TNF-α and IL-6, while increasing adiponectin levels. This compound effectively reduces reactive oxygen species (ROS) and lipid peroxidation by inhibiting the expression of NADPH oxidase components. Additionally, it down-regulates NF-κB signaling and relevant fibrotic markers, highlighting its potential applications in studying type 2 diabetes and associated complications in hepatic and pancreatic tissues.
7-O-Galloyl-D-sedoheptulose is a polyphenolic compound recognized for its antioxidant, anti-inflammatory, and anti-fibrotic properties. It lowers serum levels of glucose, leptin, insulin, and pro-inflammatory cytokines such as TNF-α and IL-6, while increasing adiponectin levels. This compound effectively reduces reactive oxygen species (ROS) and lipid peroxidation by inhibiting the expression of NADPH oxidase components. Additionally, it down-regulates NF-κB signaling and relevant fibrotic markers, highlighting its potential applications in studying type 2 diabetes and associated complications in hepatic and pancreatic tissues.
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