ALR2-IN-10

Catalog No.: A43646
Aldose Reductase 2 Inhibitor
ALR2-IN-10 is an inhibitor of Aldose Reductase 2, exhibiting a modest inhibition rate of 6% at a concentration of 27 μM. This compound is relevant for research related to diabetic complications, providing insights into the pharmacological modulation of glucose metabolism and related pathways. Suitable for studies exploring the therapeutic potential of targeting aldose reductase in diabetes-related tissue damage.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionALR2-IN-10 is an inhibitor of Aldose Reductase 2, exhibiting a modest inhibition rate of 6% at a concentration of 27 μM. This compound is relevant for research related to diabetic complications, providing insights into the pharmacological modulation of glucose metabolism and related pathways. Suitable for studies exploring the therapeutic potential of targeting aldose reductase in diabetes-related tissue damage.
Product Information
Catalog NumA43646
FormulaC21H15NO2
Molecular Weight313.35
CAS Number135-64-8
SMILESOC1=C(C(NC2=CC3=CC=CC=C3C=C2)=O)C=C4C=CC=CC4=C1
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