Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2

Catalog No.: A51852
HIV-1 Protease Substrate
Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate specifically designed for assessing the activity of HIV-1 protease. This compound exhibits a strong interaction with the enzyme, facilitating the measurement of protease activity in research applications related to HIV-1 pathogenesis and antiviral drug development. Its utility in protease assays makes it a valuable tool for studying HIV-1 enzymatic function and evaluating potential therapeutic interventions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionArg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate specifically designed for assessing the activity of HIV-1 protease. This compound exhibits a strong interaction with the enzyme, facilitating the measurement of protease activity in research applications related to HIV-1 pathogenesis and antiviral drug development. Its utility in protease assays makes it a valuable tool for studying HIV-1 enzymatic function and evaluating potential therapeutic interventions.
Product Information
Catalog NumA51852
FormulaC40H66N12O11
Molecular Weight891.03
CAS Number130877-92-8
SequenceArg-Val-{Nle-p-nitro}-Phe-Glu-Ala-{Nle}-NH2
Sequence shorteningRV-{Nle-p-nitro}-Phe-EA-{Nle}-NH2
SMILESO=[N+](C(C=C1)=CC=C1C[C@H](NC([C@H](CCCC)NC([C@H](C(C)C)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@H](C(N)=O)CCCC)=O)=O)=O)[O-]
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