Belinostat (PXD101)

Catalog No.: A10122

HDAC inhibitor

Belinostat (PXD101)

Belinostat (PXD101) Chemical Structure

CAS NO. 414864-00-9

Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $60.00

Special Price $48.00

50 mg

Regular Price: $200.00

Special Price $160.00

100 mg

Regular Price: $300.00

Special Price $240.00

200 mg

Regular Price: $500.00

Special Price $400.00

10mM * 1mL in DMSO

Regular Price: $78.00

Special Price $62.40

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Shariful Islam, .et al. Resistance to histone deacetylase inhibitors confers hypersensitivity to oncolytic reovirus therapy, Blood Adv, 2020, 4(20): 5297-5310 PMID: 33108458
  • l

Biological Activity

Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.
Targets
HDAC (Cell-free assay)
27 nM
In vitro (25°C) DMSO 56 mg/mL (175.9 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+ddH2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.41 mL 157.04 mL 314.07 mL
0.5 mM 6.28 mL 31.41 mL 62.81 mL
1 mM 3.14 mL 15.7 mL 31.41 mL
5 mM 0.63 mL 3.14 mL 6.28 mL

*The above data is based on the productmolecular weight 318.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10122
Actions Inhibitor
CAS No. 414864-00-9
Formula C15H14N2O4S
M. Wt 318.4
Purity >98%
Synonyms PX105684
SMILES C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Belinostat (PXD101) | Belinostat (PXD101) Supplier | purchase | cost | manufacturer | order | distributor | buy 414864-00-9| 414864-00-9 Supplier | purchase 414864-00-9 | 414864-00-9 cost | 414864-00-9 manufacturer | order 414864-00-9 | 414864-00-9 distributor
Rewards