Belinostat (PXD101)

Catalog No.: A10122

HDAC inhibitor

Belinostat (PXD101) Chemical Structure

CAS NO. 414864-00-9

Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.

Availability: In stock

Package Price Qty
10 mg
$60.00
50 mg
$200.00
100 mg
$300.00
200 mg
$500.00
10mM * 1mL in DMSO
$78.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.
Targets
HDAC (Cell-free assay)
27 nM
In vitro (25°C) DMSO 64 mg/mL (201.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 12 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.41 mL 157.04 mL 314.07 mL
0.5 mM 6.28 mL 31.41 mL 62.81 mL
1 mM 3.14 mL 15.7 mL 31.41 mL
5 mM 0.63 mL 3.14 mL 6.28 mL

*The above data is based on the productmolecular weight 318.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10122
Actions Inhibitor
M. Wt 318.4
Formula C15H14N2O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 414864-00-9
Synonyms PX105684
SMILES C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO

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