Belinostat (PXD101)

Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.
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Belinostat 10mg
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Belinostat 200mg
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Belinostat (PXD101) 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's Belinostat (PXD101) has been cited by 1 publications
  • Shariful Islam, .et al. , Blood Adv, 2020, 4(20): 5297-5310 PMID: 33108458
  • Biological Activity
    Discription Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.
    Target Value
    Product Information
    Catalog Num A10122
    Formula C15H14N2O4S
    Molecular Weight 318.4
    CAS Number 414864-00-9
    SMILES C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
    Synonyms PX105684

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 56 mg/mL (175.9 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.41 mL 157.04 mL 314.07 mL
    0.5 mM 6.28 mL 31.41 mL 62.81 mL
    1 mM 3.14 mL 15.7 mL 31.41 mL
    5 mM 0.63 mL 3.14 mL 6.28 mL
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