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BET-IN-15

Catalog No.: A40478
BET Inhibitor
BET-IN-15 is a potent bromodomain and extraterminal (BET) inhibitor that targets BRD4 with IC50 values of 0.64 nM and 0.25 nM for BRD4-BD1 and BRD4-BD2, respectively. This compound exhibits significant antiproliferative activity, making it an important tool for studying the role of BET proteins in cancer and other diseases. Researchers can utilize BET-IN-15 in investigations of transcriptional regulation and the therapeutic potential of BET inhibition in oncology.
BET-IN-15 2408994-22-7 BET Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBET-IN-15 is a potent bromodomain and extraterminal (BET) inhibitor that targets BRD4 with IC50 values of 0.64 nM and 0.25 nM for BRD4-BD1 and BRD4-BD2, respectively. This compound exhibits significant antiproliferative activity, making it an important tool for studying the role of BET proteins in cancer and other diseases. Researchers can utilize BET-IN-15 in investigations of transcriptional regulation and the therapeutic potential of BET inhibition in oncology.
Product Information
Catalog NumA40478
FormulaC21H18F2N4O3S
Molecular Weight444.45
CAS Number2408994-22-7
SMILESO=C1C2=C(C(C3=C(OC4=CC=C(C=C4F)F)C=CC(N=S(C)(C)=O)=N3)=CN1C)C=CN2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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