BETi-211 is a potent BET inhibitor with a Ki value of less than 1 nM. It selectively inhibits the growth of triple-negative breast cancer (TNBC) cell lines, exhibiting an IC50 of less than 1 μM. BETi-211 effectively induces degradation of BET proteins, leading to significant suppression of tumor growth in xenograft models of breast cancer, making it a valuable tool for cancer research and therapeutic development.
BETi-211 is a potent BET inhibitor with a Ki value of less than 1 nM. It selectively inhibits the growth of triple-negative breast cancer (TNBC) cell lines, exhibiting an IC50 of less than 1 μM. BETi-211 effectively induces degradation of BET proteins, leading to significant suppression of tumor growth in xenograft models of breast cancer, making it a valuable tool for cancer research and therapeutic development.
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