BGSBD

Catalog No.: A45148
SNAP tag Fluorescent Probe
BGSBD is a SNAP-tag-based fluorescent probe that exhibits excitation and emission maxima at 435 nm and 516 nm, respectively. This probe is engineered with the environmentally sensitive SBD fluorescent group, allowing for direct protein labeling in live cells without the need for washing steps. BGSBD demonstrates a significant fluorescence enhancement of 280-fold upon labeling, leveraging the hydrophobic binding pocket of the SNAP-tag protein. This unique characteristic makes it a valuable tool for real-time visualization and monitoring of protein dynamics within cellular environments.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBGSBD is a SNAP-tag-based fluorescent probe that exhibits excitation and emission maxima at 435 nm and 516 nm, respectively. This probe is engineered with the environmentally sensitive SBD fluorescent group, allowing for direct protein labeling in live cells without the need for washing steps. BGSBD demonstrates a significant fluorescence enhancement of 280-fold upon labeling, leveraging the hydrophobic binding pocket of the SNAP-tag protein. This unique characteristic makes it a valuable tool for real-time visualization and monitoring of protein dynamics within cellular environments.
Product Information
Catalog NumA45148
FormulaC23H24N10O5S
Molecular Weight552.57
CAS Number1622078-12-9
SMILESCNC1=CC=C(C2=NON=C12)S(=O)(N(CC(NCC3=CC=C(C=C3)COC4=NC(N)=NC5=C4N=CN5)=O)C)=O
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