Biotin-TEG-ATFBA is a click chemistry reagent featuring a perfluorophenylazide moiety. This compound is known for forming a highly stable azene intermediate, facilitating insertion and addition reactions with moderate to good yields following photolysis. It possesses an azide functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Biotin-TEG-ATFBA can participate in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN-tagged substrates, making it a valuable tool for bioconjugation and labeling applications in chemical biology.
Biotin-TEG-ATFBA is a click chemistry reagent featuring a perfluorophenylazide moiety. This compound is known for forming a highly stable azene intermediate, facilitating insertion and addition reactions with moderate to good yields following photolysis. It possesses an azide functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Biotin-TEG-ATFBA can participate in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN-tagged substrates, making it a valuable tool for bioconjugation and labeling applications in chemical biology.
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