BRCA2-RAD51-IN-1

Catalog No.: A56941
BRCA2-RAD51 Inhibitor
BRCA2-RAD51-IN-1 is a specific inhibitor of the BRCA2-RAD51 complex, demonstrated to have an EC50 value of 28 μM. This compound exhibits notable antitumor activity, making it a valuable tool for research into cancer treatments targeting DNA repair mechanisms. Its application in studies of BRCA-mediated tumorigenesis helps elucidate potential therapeutic strategies for cancers associated with BRCA2 mutations.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBRCA2-RAD51-IN-1 is a specific inhibitor of the BRCA2-RAD51 complex, demonstrated to have an EC50 value of 28 μM. This compound exhibits notable antitumor activity, making it a valuable tool for research into cancer treatments targeting DNA repair mechanisms. Its application in studies of BRCA-mediated tumorigenesis helps elucidate potential therapeutic strategies for cancers associated with BRCA2 mutations.
Product Information
Catalog NumA56941
FormulaC13H7BrF3N3O
Molecular Weight358.11
CAS Number2830213-53-9
SMILESBrC1=CC=CC(C(NC2=CC(C(F)(F)F)=NN23)=CC3=O)=C1
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