BRD4-BD1/2-IN-2

Catalog No.: A40506
BRD4 BD2 Inhibitor
BRD4-BD1/2-IN-2 is a highly selective inhibitor targeting the BD2 domain of BRD4, demonstrating IC50 values of less than 0.5 nM for BRD4 BD2 and approximately 300 nM for BRD4 BD1. This compound exhibits significant biological activity in modulating BRD4-related pathways, making it a valuable tool for research in oncology and epigenetic regulation. Its potency and specificity support further exploration of BRD4 as a therapeutic target in various diseases.
Grouped product items
Size Price Stock Qty
25mg
$1,800.00
In stock
50mg
$2,285.00
In stock
100mg
$2,815.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBRD4-BD1/2-IN-2 is a highly selective inhibitor targeting the BD2 domain of BRD4, demonstrating IC50 values of less than 0.5 nM for BRD4 BD2 and approximately 300 nM for BRD4 BD1. This compound exhibits significant biological activity in modulating BRD4-related pathways, making it a valuable tool for research in oncology and epigenetic regulation. Its potency and specificity support further exploration of BRD4 as a therapeutic target in various diseases.
Product Information
Catalog NumA40506
FormulaC30H33N5O4
Molecular Weight527.61
CAS Number2743464-27-7
SMILESO=C(C1=CC(C(C2=CC3=NN(CC(C)(C)O)C=C3C=C2OC4=C(C)C=CC=C4C)=CN5C)=C(N1)C5=O)NCC
Useful Calculator

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