BRD4 D1-IN-1 is a selective inhibitor of the BRD4 D1 domain, demonstrating an IC50 of less than 0.092 µM and an affinity of 18 nM. This compound exhibits over 500-fold selectivity for BRD4 D1 compared to BRD2 D1 and BRD4 D2, as determined by isothermal titration calorimetry (ITC). BRD4 D1-IN-1 is primarily used in research related to cancer and inflammatory diseases, providing insights into the role of BRD4 in transcriptional regulation.
BRD4 D1-IN-1 is a selective inhibitor of the BRD4 D1 domain, demonstrating an IC50 of less than 0.092 µM and an affinity of 18 nM. This compound exhibits over 500-fold selectivity for BRD4 D1 compared to BRD2 D1 and BRD4 D2, as determined by isothermal titration calorimetry (ITC). BRD4 D1-IN-1 is primarily used in research related to cancer and inflammatory diseases, providing insights into the role of BRD4 in transcriptional regulation.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
