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C004019

Catalog No.: A24663
Tau Scavenger
C004019 is a small-molecule PROTAC designed to target tau, functioning as a tau scavenger. This compound effectively recruits tau and E3 ligase, promoting the ubiquitination and proteasome-dependent degradation of tau proteins. C004019 has demonstrated the potential to enhance synaptic and cognitive functions in models of Alzheimer's disease, making it a valuable tool for research into Alzheimer's and tau protein-related pathologies.
C004019 2417159-57-8 Tau Scavenger
Grouped product items
Size Price Stock Qty
1mg
$210.00
In stock
5mg
$530.00
In stock
10mg
$790.00
In stock
25mg
$1,160.00
In stock
50mg
$1,540.00
In stock
100mg
$2,025.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionC004019 is a small-molecule PROTAC designed to target tau, functioning as a tau scavenger. This compound effectively recruits tau and E3 ligase, promoting the ubiquitination and proteasome-dependent degradation of tau proteins. C004019 has demonstrated the potential to enhance synaptic and cognitive functions in models of Alzheimer's disease, making it a valuable tool for research into Alzheimer's and tau protein-related pathologies.
Product Information
Catalog NumA24663
FormulaC49H70N12O9S2
Molecular Weight1035.29
CAS Number2417159-57-8
SMILESO=C(N1[C@H](C[C@@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCOCCOCCNC(CN(C4=NC(N5CCN(CCC5)C(C)=O)=NC(NCCC6=CC=CS6)=N4)C)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Neuronal Signaling > Tau Protein