Calcein sodium salt is a fluorescent dye that serves as a self-quenching probe, primarily utilized for assessing lipid vesicle leakage. It acts as a complexometric indicator for titrating calcium ions with EDTA and can be employed in the fluorometric determination of calcium concentration. Unlike its cell-permeable counterpart, Calcein-AM, Calcein itself does not penetrate intact cell membranes, making it suitable for in vitro studies. Additionally, it is useful as a model compound for evaluating the efficiency and bioavailability of drug delivery systems.
Calcein sodium salt is a fluorescent dye that serves as a self-quenching probe, primarily utilized for assessing lipid vesicle leakage. It acts as a complexometric indicator for titrating calcium ions with EDTA and can be employed in the fluorometric determination of calcium concentration. Unlike its cell-permeable counterpart, Calcein-AM, Calcein itself does not penetrate intact cell membranes, making it suitable for in vitro studies. Additionally, it is useful as a model compound for evaluating the efficiency and bioavailability of drug delivery systems.
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