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Calpain substrate

Catalog No.: A77331
Substrate
Calpain substrate is a fluorogenic substrate specifically designed for the assessment of calpain enzymatic activity. It is membrane non-permeable, ensuring precise measurement of calpain activity in biological samples. This reagent is suitable for applications in cellular signaling research and studies investigating calpain's role in various physiological and pathological processes.
Calpain substrate 728005-83-2 Substrate
Grouped product items
Size Price Stock Qty
1mg
$105.00
In stock
5mg
$260.00
In stock
10mg
$435.00
In stock
25mg
$720.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCalpain substrate is a fluorogenic substrate specifically designed for the assessment of calpain enzymatic activity. It is membrane non-permeable, ensuring precise measurement of calpain activity in biological samples. This reagent is suitable for applications in cellular signaling research and studies investigating calpain's role in various physiological and pathological processes.
Product Information
Catalog NumA77331
FormulaC80H114N20O18S
Molecular Weight1675.95
CAS Number728005-83-2
Sequence{DABCYL}-Thr-Pro-Leu-Lys-Ser-Pro-Pro-Pro-Ser-Pro-Arg-{EDANS}
Sequence shortening{DABCYL}-TPLKSPPPSPR-{EDANS}
SMILESS(=O)(=O)(O)C=1C2=C(C(NCCNC([C@@H](NC(=O)[C@H]3N(C([C@@H](NC(=O)[C@H]4N(C(=O)[C@H]5N(C(=O)[C@H]6N(C([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]7N(C([C@@H](NC(=O)C8=CC=C(N=NC9=CC=C(N(C)C)C=C9)C=C8)[C@@H](C)O)=O)CCC7)CC(C)C)=O)CCCCN)=O)CO)=O)CCC6)CCC5)CCC4)CO)=O)CCC3)CCCNC(=N)N)=O)=CC=C2)C=CC1
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Proteases > Proteasome