Canagliflozin hemihydrate

Catalog No.: A16817

SGLT2 inhibitor

Canagliflozin hemihydrate

Canagliflozin hemihydrate Chemical Structure

CAS NO. 928672-86-0

Canagliflozin hemihydrate is the hemihydrate form of canagliflozin, which is a SGLT2 inhibitor with IC50 of 2.2 nM for hSGLT2 in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.

Availability: In stock

Package Price Qty
5 mg
$45.00
10 mg
$68.00
50 mg
$100.00
100 mg
$130.00
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Biological Activity

Canagliflozin hemihydrate is the hemihydrate form of canagliflozin, which is a SGLT2 inhibitor with IC50 of 2.2 nM for hSGLT2 in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.02 mL 55.12 mL 110.25 mL
0.5 mM 2.2 mL 11.02 mL 22.05 mL
1 mM 1.1 mL 5.51 mL 11.02 mL
5 mM 0.22 mL 1.1 mL 2.2 mL

*The above data is based on the productmolecular weight 907.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16817
Actions Inhibitor
M. Wt 907.05
Formula C48H52F2O11S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 928672-86-0
Synonyms JNJ 28431754; JNJ-28431754; JNJ28431754; TA 7284; TA-7284; TA7284; JNJ-24831754-ZAE; JNJ-28431754-AAA
SMILES O[[email protected]]1C(O[[email protected]@H]([[email protected]]([[email protected]@H]1O)O)CO)C2=CC=C(C(CC3=CC=C(S3)C4=CC=C(C=C4)F)=C2)C.[H]O[H].O[[email protected]]5C(O[[email protected]@H]([[email protected]]([[email protected]@H]5O)O)CO)C6=CC=C(C(CC7=CC=C(S7)C8=CC=C(C=C8)F)=C6)C

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