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- Jianwei Dou, .et al. Development and evaluation of poly adenosine 5'-diphosphate-ribose polymerase 1 immobilization-based receptor chromatography, J Sep Sci, 2020, Dec 4 PMID: 33275824
Biological Activity
Carboplatin is a chemotherapy drug used against some forms of cancer (mainly ovarian carcinoma, lung, head and neck cancers). Cisplatin and carboplatin, as well as oxaliplatin, interact with DNA, akin to the mechanism of alkylating agents.
Targets
| DNA synthesis (A2780, SKOV-3, IGROV-1, HX62 cells) | ||||
| In vitro | DMSO | Insoluble | |
| Water | Warmed: 14 mg/mL (37.71 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.93 mL | 134.66 mL | 269.32 mL |
| 0.5 mM | 5.39 mL | 26.93 mL | 53.86 mL |
| 1 mM | 2.69 mL | 13.47 mL | 26.93 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.39 mL |
*The above data is based on the productmolecular weight 371.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10182 |
|---|---|
| CAS No. | 41575-94-4 |
| Formula | C6H12N2O4Pt |
| M. Wt | 371.3 |
| Purity | >98% |
| Synonyms | Paraplatin |
| SMILES | C1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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