Oxaliplatin (Eloxatin)

Catalog No.: A10346

DNA/RNA Synthesis inhibitor

Oxaliplatin (Eloxatin)

Oxaliplatin (Eloxatin) Chemical Structure

CAS NO. 61825-94-3

Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. In vivo studies showed that Oxaliplatin has anti-tumor activity against colon carcinoma through its (non-targeted) cytotoxic effects.

Availability: In stock

Package Price Qty
50 mg
$40.00
100 mg
$70.00
200 mg
$120.00
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  • Tatsuya Usui, .et al. Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture, Int J Mol Sci, 2018, Apr; 19(4): 1098 PMID: 29642386
  • Shimokawa M, .et al. Visualization and targeting of LGR5+ human colon cancer stem cells, Nature, 2017, May 11;545(7653):187-192 PMID: 28355176
  • Eri Takiguchi, .et al. Growth inhibitory effect of the Src inhibitor dasatinib in combination with anticancer agents on uterine cervical adenocarcinoma cells, Exp Ther Med, 2017, Nov; 14(5): 4293-4299 PMID: 29067110

Biological Activity

Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. In vivo studies showed that Oxaliplatin has anti-tumor activity against colon carcinoma through its (non-targeted) cytotoxic effects.
Targets
DNA synthesis (RT4, TCCSUP, A2780, HT-29, U-373MG, U-87MG, SK-MEL-2, HT-144 cells)
In vitro DMSO <1 mg/mL (<1 mM)
Water 11 mg/mL
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.17 mL 125.85 mL 251.7 mL
0.5 mM 5.03 mL 25.17 mL 50.34 mL
1 mM 2.52 mL 12.58 mL 25.17 mL
5 mM 0.5 mL 2.52 mL 5.03 mL

*The above data is based on the productmolecular weight 397.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10346
Actions Inhibitor
M. Wt 397.3
Formula C8H14N2O4Pt
Solubility Water
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 61825-94-3
SMILES O=C3O[Pt]1(N[[email protected]@H]2CCCC[[email protected]]2N1)OC3=O

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