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Oxaliplatin (Eloxatin)

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DNA/RNA Synthesis inhibitor

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Catalog No. A10346

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Oxaliplatin 50mg A10346-50

Regular Price: $40.00

Special Price: $36.00

Oxaliplatin 100mg A10346-100

Regular Price: $70.00

Special Price: $63.00

Oxaliplatin 200mg A10346-200

Regular Price: $120.00

Special Price: $108.00

Oxaliplatin (Eloxatin) 10mM * 1mL in DMSO A10346-10mM-D

Regular Price: $62.00

Special Price: $55.80

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. In vivo studies showed that Oxaliplatin has anti-tumor activity against colon carcinoma through its (non-targeted) cytotoxic effects.

Oxaliplatin (Eloxatin)

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Publications citing Adooq Products
Oxaliplatin (Eloxatin) Citations (3)
  • Tatsuya Usui,et al. Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture, Int J Mol Sci, 2018, Apr; 19(4): 1098 29642386
  • Shimokawa M,et al. Visualization and targeting of LGR5+ human colon cancer stem cells, Nature, 2017, May 11;545(7653):187-192 28355176
  • Eri Takiguchi,et al. Growth inhibitory effect of the Src inhibitor dasatinib in combination with anticancer agents on uterine cervical adenocarcinoma cells, Exp Ther Med, 2017, Nov; 14(5): 4293-4299 29067110

Chemical Information

Catalog Num A10346
Actions Inhibitor
M. Wt 397.3
Formula C8H14N2O4Pt
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 61825-94-3
Synonyms N/A
SMILES code O=C3O[Pt]1(N[[email protected]@H]2CCCC[[email protected]]2N1)OC3=O
Chemical Name [(1R,2R)-cyclohexane-1,2-diamine](ethanedioato-O,O')platinum(II)

Biological Activity

Description
Oxaliplatin is a platinum-based antineoplastic agent that is used in cancer chemotherapy. In vivo studies showed that Oxaliplatin has anti-tumor activity against colon carcinoma through its (non-targeted) cytotoxic effects.
Targets
DNA synthesis (RT4, TCCSUP, A2780, HT-29, U-373MG, U-87MG, SK-MEL-2, HT-144 cells)

Solubility

Solubility (25°C)* In vitro DMSO 14 mg/mL (35.23 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.17 mL 125.85 mL 251.7mL
0.5 mM 5.03 mL 25.17 mL 50.34 mL
1 mM 2.52 mL 12.58 mL 25.17 mL
5 mM 0.5 mL 2.52 mL 5.03 mL

*The above data is based on the productmolecular weight 397.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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