CHF-6366 is a potent M3 muscarinic antagonist and β2-adrenergic receptor agonist, exhibiting pKi values of 10.4 and 11.4, respectively. Additionally, it serves as a weak calcium channel inhibitor with an IC50 of approximately 50 μM. CHF-6366 effectively inhibits bronchoconstriction in guinea pig models, making it a valuable tool for research into chronic obstructive pulmonary disease (COPD) and related respiratory conditions.
CHF-6366 is a potent M3 muscarinic antagonist and β2-adrenergic receptor agonist, exhibiting pKi values of 10.4 and 11.4, respectively. Additionally, it serves as a weak calcium channel inhibitor with an IC50 of approximately 50 μM. CHF-6366 effectively inhibits bronchoconstriction in guinea pig models, making it a valuable tool for research into chronic obstructive pulmonary disease (COPD) and related respiratory conditions.
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