Chlojaponilactone B is a lindenane-type sesquiterpenoid known for its anti-inflammatory properties. This compound functions by inhibiting Toll-like receptor 4 (TLR4), leading to a decrease in reactive oxygen species (ROS) production and downregulation of the NF-κB pathway. Consequently, it reduces the expression of pro-inflammatory cytokines, including iNOS, nitric oxide (NO), COX-2, IL-6, and TNF-α. Chlojaponilactone B is a valuable tool for research into inflammation and related pathways.
Chlojaponilactone B is a lindenane-type sesquiterpenoid known for its anti-inflammatory properties. This compound functions by inhibiting Toll-like receptor 4 (TLR4), leading to a decrease in reactive oxygen species (ROS) production and downregulation of the NF-κB pathway. Consequently, it reduces the expression of pro-inflammatory cytokines, including iNOS, nitric oxide (NO), COX-2, IL-6, and TNF-α. Chlojaponilactone B is a valuable tool for research into inflammation and related pathways.
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