Chlorpromazine

Catalog No.: A17763
Antipsychotic Agent
Chlorpromazine is an orally active antipsychotic agent that primarily antagonizes D2 dopamine and 5-HT2A serotonin receptors, making it effective in the treatment of schizophrenia and other psychiatric conditions. Additionally, chlorpromazine exhibits anti-cancer properties through mechanisms such as inhibition of tumor proliferation, induction of autophagy, cell cycle arrest at the G2-M phase, and suppression of tumor growth and metastasis. It also blocks hNav1.7 and HERG potassium channels, which has implications for analgesic and cardiac arrhythmia research. Furthermore, chlorpromazine inhibits clathrin-mediated endocytosis, expanding its potential applications in biomedical research.
Grouped product items
Size Price Stock Qty
10mg
$30.00
In stock
25mg
$55.00
In stock
50mg
$80.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionChlorpromazine is an orally active antipsychotic agent that primarily antagonizes D2 dopamine and 5-HT2A serotonin receptors, making it effective in the treatment of schizophrenia and other psychiatric conditions. Additionally, chlorpromazine exhibits anti-cancer properties through mechanisms such as inhibition of tumor proliferation, induction of autophagy, cell cycle arrest at the G2-M phase, and suppression of tumor growth and metastasis. It also blocks hNav1.7 and HERG potassium channels, which has implications for analgesic and cardiac arrhythmia research. Furthermore, chlorpromazine inhibits clathrin-mediated endocytosis, expanding its potential applications in biomedical research.
Product Information
Catalog NumA17763
FormulaC17H19ClN2S
Molecular Weight318.86
CAS Number50-53-3
SMILESCN(C)CCCN1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13
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