Chlovalicin is an antifungal compound derived from the Sporothrix sp. FO-4649 strain, demonstrating significant anticancer properties. It effectively inhibits the proliferation of L6-dependent MH60 cells in the presence of IL-6, with an IC50 value of 7.5 μM, and also shows inhibitory effects on B16 melanoma cells at an IC50 of 38 μM. Additionally, Chlovalicin exhibits potential in modulating osteoclastogenesis, making it a valuable reagent for cancer research and studies on bone metabolism.
Chlovalicin is an antifungal compound derived from the Sporothrix sp. FO-4649 strain, demonstrating significant anticancer properties. It effectively inhibits the proliferation of L6-dependent MH60 cells in the presence of IL-6, with an IC50 value of 7.5 μM, and also shows inhibitory effects on B16 melanoma cells at an IC50 of 38 μM. Additionally, Chlovalicin exhibits potential in modulating osteoclastogenesis, making it a valuable reagent for cancer research and studies on bone metabolism.
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