Total item
Cart Subtotal
$0.00 Biological Activity
CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 7.01 mL | 35.05 mL | 70.1 mL |
| 0.5 mM | 1.4 mL | 7.01 mL | 14.02 mL |
| 1 mM | 0.7 mL | 3.5 mL | 7.01 mL |
| 5 mM | 0.14 mL | 0.7 mL | 1.4 mL |
*The above data is based on the productmolecular weight 1426.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18388 |
|---|---|
| M. Wt | 1426.61 |
| Formula | C68H103N11O22 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2270986-66-6 |
| SMILES | OCC(COC(N(C)CCN(C)C(OCC(C=C1)=CC=C1NC([[email protected]](CCCCNC(OC(C)(C)C)=O)NC([[email protected]@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN2C=C(CNC(CCCCCN3C(C=CC3=O)=O)=O)N=N2)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy CL2 Linker | CL2 Linker Supplier | purchase | cost | manufacturer | order | distributor | buy 2270986-66-6| 2270986-66-6 Supplier | purchase 2270986-66-6 | 2270986-66-6 cost | 2270986-66-6 manufacturer | order 2270986-66-6 | 2270986-66-6 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.