TCO

JQ1-TCO (JQ1-trans-cyclooctene) is a derivative of JQ1, a BET inhibitor, modified for click chemistry applications. It serves as a molecular probe for in vitro and in vivo studies.

TcO-ABX474 is a potent inhibitor of prostate-specific membrane antigen (PSMA), exhibiting a Kd value of 6.1 nM. It effectively inhibits the growth and metastasis of prostate cancer cells, making it a valuable tool for research in prostate cancer biology. This compound is suitable for studies investigating PSMA-mediated pathways and the development of targeted therapies for prostate cancer.