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Form	MW
CP-470711 This page	358.44
(6S)-CP-470711	358.44

CP-470711

SDH Inhibitor

CP-470711 is a potent and selective inhibitor of sorbitol dehydrogenase (SDH), demonstrating an IC50 of 10 nM for human SDH and 17 nM for rat SDH. This compound is valuable for studying chronic complications associated with type 2 diabetes mellitus, including diabetic neuropathy and nephropathy. Its oral bioavailability enables convenient administration in research applications focused on metabolic disorders and their related pathologies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	300548-99-6
Applications	SDH Inhibitor
Formula	C₁₈H₂₆N₆O₂
Molecular Weight	358.44
SMILES	C[C@@H]1N(C2=NC([C@H](O)C)=NC=C2)[C@@H](CN(C3=NC([C@H](O)C)=NC=C3)C1)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.