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Myosin

Myosin inhibitors and activators act on the actin-based motor proteins of muscle and non-muscle cells. Myosins hydrolyze adenosine triphosphate (ATP) and convert that chemical energy into movement along actin filaments. Blebbistatin was introduced in 2003 as a selective inhibitor of non-muscle myosin II and is used to study cytokinesis and cortical tension. The catalogue lists it as (-)-Blebbistcitin together with para-Nitroblebbistatin, a photostable analog suited to imaging experiments. Omecamtiv mecarbil works in the opposite direction and accelerates the cardiac myosin ATPase cycle. ML 7 hydrochloride and ML-9 hydrochloride act upstream on myosin light chain kinase, as does the neighboring MLCK category.

3 Items

  • 4-Hydroxyacetophenone
    Cat. No.
    A15757
    CAS No.
    99-93-4

    4-Hydroxyacetophenone

    Synonyms: P-hydroxyacetophenone

    4-Hydroxyacetophenone is a potent myosin activator that has demonstrated hepatoprotective and choleretic properties. This compound exhibits antiviral and anti-inflammatory activities, particularly against hepatitis B virus, and is known to inhibit cancer cell adhesion, invasion, and migration through actin remodeling. Its diverse biological activities make 4-Hydroxyacetophenone a valuable reagent for research in inflammatory diseases and cancer studies.

    In stock View Details
    100 mg
    $25.00
    500 mg
    $30.00
    All 2 sizes
  • Danicamtiv
    Cat. No.
    A57583
    CAS No.
    1970972-74-7

    Danicamtiv

    Synonyms: MYK-491

    Danicamtiv is a selective allosteric activator of cardiac myosin, serving as a cardiac inotropic agent. It enhances cardiac systolic function while maintaining mechanical efficiency, making it a valuable tool for research on heart failure and myocardial contractility. This compound is instrumental in studying the modulation of cardiac contractile function and understanding its implications in cardiovascular diseases.

    In stock View Details
    1 mg
    $110.00
    5 mg
    $235.00
    All 6 sizes

3 Items

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