CK-1827452 (Omecamtiv mecarbil)

Catalog No.: A11206

Myosin activator

CK-1827452 (Omecamtiv mecarbil) Chemical Structure

CAS NO. 873697-71-3

CK-1827452 is a selective cardiac specific myosin activator.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$160.00
50 mg
$480.00
100 mg
$880.00
10mM * 1mL in DMSO
$131.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

CK-1827452 is a selective cardiac specific myosin activator.
Targets
Myosin ATPase
In vitro (25°C) DMSO 80 mg/mL (199.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.91 mL 124.55 mL 249.11 mL
0.5 mM 4.98 mL 24.91 mL 49.82 mL
1 mM 2.49 mL 12.46 mL 24.91 mL
5 mM 0.5 mL 2.49 mL 4.98 mL

*The above data is based on the productmolecular weight 401.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11206
Actions Activator
M. Wt 401.43
Formula C20H24FN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 873697-71-3
Synonyms CK1827452, Omecamtiv Mecarbil
SMILES CC1=NC=C(C=C1)NC(=O)NC2=CC=CC(=C2F)CN3CCN(CC3)C(=O)OC

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