Dabrafenib-d9 is a deuterium-labeled analog of the selective ATP-competitive inhibitor Dabrafenib, which targets Raf kinases. This reagent exhibits potent inhibition, with IC50 values of 5 nM for C-Raf and 0.6 nM for B-RafV600E. Dabrafenib-d9 is primarily utilized in pharmacokinetic studies and metabolic research, enhancing the understanding of Dabrafenib's dynamics and behavior in biological systems.
Dabrafenib-d9 is a deuterium-labeled analog of the selective ATP-competitive inhibitor Dabrafenib, which targets Raf kinases. This reagent exhibits potent inhibition, with IC50 values of 5 nM for C-Raf and 0.6 nM for B-RafV600E. Dabrafenib-d9 is primarily utilized in pharmacokinetic studies and metabolic research, enhancing the understanding of Dabrafenib's dynamics and behavior in biological systems.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
