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DBCO-PEG3-Glu-Val-Cit-PABC-MMAE

Catalog No.: A41539
Drug-linker Conjugate
DBCO-PEG3-Glu-Val-Cit-PABC-MMAE is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound incorporates the potent tubulin inhibitor Monomethyl auristatin E (MMAE), facilitating targeted delivery in cancer therapeutics. Its structural features enable effective synthesis of dual-drug ADCs, enhancing cytotoxic efficacy while minimizing off-target effects.
DBCO-PEG3-Glu-Val-Cit-PABC-MMAE 2861998-23-2 Drug-linker Conjugate
Grouped product items
Size Price Stock Qty
1mg
$695.00
In stock
5mg
$1,790.00
In stock
10mg
$2,940.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBCO-PEG3-Glu-Val-Cit-PABC-MMAE is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound incorporates the potent tubulin inhibitor Monomethyl auristatin E (MMAE), facilitating targeted delivery in cancer therapeutics. Its structural features enable effective synthesis of dual-drug ADCs, enhancing cytotoxic efficacy while minimizing off-target effects.
Product Information
Catalog NumA41539
FormulaC90H129N13O21
Molecular Weight1729.06
CAS Number2861998-23-2
SMILESO=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC(COCCOCCOCCNC(CCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O)=O)=O)=O)=O)=O)=O)=O
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