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Biological Activity
DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.71 mL | 158.54 mL | 317.09 mL |
| 0.5 mM | 6.34 mL | 31.71 mL | 63.42 mL |
| 1 mM | 3.17 mL | 15.85 mL | 31.71 mL |
| 5 mM | 0.63 mL | 3.17 mL | 6.34 mL |
*The above data is based on the productmolecular weight 315.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18470 |
|---|---|
| Actions | Activator |
| CAS No. | 1269365-82-3 |
| Formula | C20H17N3O |
| M. Wt | 315.37 |
| Purity | >98% |
| SMILES | CC1=CC(C)=C(NC(C(C2=C(C3=CC=CC=C3)N=CN2)=C4)=O)C4=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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