DPLG3

Name: DPLG3
Brand: Adooq Bioscience
SKU: A77316
Rating: 5 (288 reviews)

Catalog No.: A77316

Immunoproteasome β5i Subunit Inhibitor

DPLG3 is a selective inhibitor of the immunoproteasome β5i subunit, demonstrating an IC50 of 4.5 nM. It effectively inhibits the mouse i-20S proteasome with an IC50 value of 9.4 nM. DPLG3 is capable of downregulating the protein levels of NF-κB p50 and p65, highlighting its potential in the study of immune-related diseases and therapeutic applications.

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DPLG3 1801379-22-5 Immunoproteasome β5i Subunit Inhibitor

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Grouped product items
Size	Price	Stock
5mg	$255.00	In stock
10mg	$410.00	In stock
25mg	$825.00	In stock
50mg	$1,285.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	DPLG3 is a selective inhibitor of the immunoproteasome β5i subunit, demonstrating an IC50 of 4.5 nM. It effectively inhibits the mouse i-20S proteasome with an IC50 value of 9.4 nM. DPLG3 is capable of downregulating the protein levels of NF-κB p50 and p65, highlighting its potential in the study of immune-related diseases and therapeutic applications.

Product Information

Catalog Num	A77316
Formula	C37H41FN4O5
Molecular Weight	640.74
CAS Number	1801379-22-5
SMILES	C(NC([C@H](CC1=CC=C(F)C=C1)NC([C@@H](NC(CCC2=CC=CC=C2)=O)CC(NOC(C)(C)C)=O)=O)=O)C=3C4=C(C=CC3)C=CC=C4

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