Bioluminescence: Luciferins & Luciferase
This category includes luciferin substrates, luciferase enzymes and luciferase modulators for laboratory research. The selection covers D-luciferin and its salts, luciferin analogs, coelenterazine and its derivatives, firefly and bacterial luciferases, and luciferase inhibitors and an activator. These products are listed for bioluminescence and reporter-assay research. Check each product record for its intended enzyme system, substrate requirements and supporting references.
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- Cat. No.
- A13789
D-Luciferin
Synonyms: Firefly Luciferin
D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications.
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- Cat. No.
- A15897
Coelenterazine
Synonyms: CLZN
Coelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques.
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- Cat. No.
- A21476
D-Luciferin potassium salt
D-Luciferin potassium salt is the substrate of luciferases that catalyze the production of light in bioluminescent insects.
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- Cat. No.
- A21760
D-Luciferin sodium salt
Synonyms: D-(-)-Luciferin sodium salt; Firefly luciferin sodium salt
D-Luciferin sodium salt is the substrate of luciferases that catalyze the production of light in bioluminescent insects.
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- Cat. No.
- A22152
Aka Lumine
Aka Lumine, a luciferin analogue, is a luciferase substrate emitting red, green, and blue light. The longest emission wavelength of Aka Lumine is recorded at 675 nm, which is within the NIR region.
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- Cat. No.
- A39063
Luciferase activator-1
Luciferase activator-1 is a potent activator of luciferase, enhancing luciferase activity by 1.04-fold at a concentration of 50 nM. This reagent is valuable for applications in bioluminescence assays and studying gene expression, where increased luciferase activity is crucial for sensitive detection. Utilizing this compound can aid researchers in optimizing experimental conditions and improving the sensitivity of their assays.
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- Cat. No.
- A44507
ETZ
Synonyms: C3-CA-DTZ
ETZ (C3-CA-DTZ) is a novel luciferase substrate that acts as a prosubstrate activated in vivo by nonspecific esterases. This activation enhances the delivery of luciferin to the brain, facilitating advanced bioluminescent imaging studies. ETZ is particularly useful for applications in neurological research and monitoring cellular processes in live tissues.
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- Cat. No.
- B11314
L-Luciferin
L-Luciferin is an alternative substrate for the enzyme luciferase, primarily utilized for bioluminescence applications in research. It competes with firefly luciferin, influencing light production based on enzyme concentration and substrate availability. This compound is widely used in studies involving gene expression, cellular activity, and drug screening, providing valuable insights into various biological processes.
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