Fig. 1 · Structure
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EBOV-IN-11
PP1 Inhibitor
EBOV-IN-11 is a potent inhibitor of protein phosphatase 1 (PP1), exhibiting Kd values of 1.88 nM for wild-type PP1 and 8.01 nM for the quadruple-mutant variant. This compound effectively inhibits the replication and transcription of the EBOV-eGFP virus, demonstrating significant antiviral activity. EBOV-IN-11 is suitable for research applications related to Ebola virus infection and the exploration of PP1-related pathways in viral pathogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 752216-12-9 |
| Applications | PP1 Inhibitor |
| Formula | C26H25N3O6 |
| Molecular Weight | 475.50 |
| SMILES | O=C(OC(C(=O)NC(=O)N)C)C=1C=2C=CC=CC2N=C3C(=CC4=CC=C(OC)C(OC)=C4)CCC31 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.