Emodic acid

Catalog No.: A34844
Anticancer Agent
Emodic acid is an anthraquinone compound that primarily targets and inhibits the activity of NF-κB, demonstrating significant anticancer properties. It effectively reduces the proliferation of cancer cells by inhibiting the phosphorylation of key proteins such as p38, ERK, and JNK. Additionally, Emodic acid suppresses the secretion of tumor-promoting cytokines IL-1β and IL-6, as well as the expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs), thereby limiting the invasion and migration potential of cancer cells. This compound is valuable for research applications in cancer biology and therapeutic development.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
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Nature Volume 622 Issue 7982 (2023)
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Biological Activity
DescriptionEmodic acid is an anthraquinone compound that primarily targets and inhibits the activity of NF-κB, demonstrating significant anticancer properties. It effectively reduces the proliferation of cancer cells by inhibiting the phosphorylation of key proteins such as p38, ERK, and JNK. Additionally, Emodic acid suppresses the secretion of tumor-promoting cytokines IL-1β and IL-6, as well as the expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs), thereby limiting the invasion and migration potential of cancer cells. This compound is valuable for research applications in cancer biology and therapeutic development.
Product Information
Catalog NumA34844
FormulaC15H8O7
Molecular Weight300.22
CAS Number478-45-5
SMILESOC1=CC(O)=CC(C(C2=C3C(O)=CC(C(O)=O)=C2)=O)=C1C3=O
SynonymsNSC624610
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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