ENOblock (AP-III-a4)

Catalog No.: A11840

ENOblock (AP-III-a4)

ENOblock (AP-III-a4) Chemical Structure

CAS NO. 1177827-73-4

ENOblock (AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo.

Availability: In stock

Package Price Qty
2 mg
$160.00
5 mg
$240.00
10 mg
$420.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Rachel Polcyn, .et al. Enolase inhibition alters metabolic hormones and inflammatory factors to promote neuroprotection in spinal cord injury, Neurochem Int, 2020, Jul 7;104788 PMID: 32650031
  • Yakarsonmez S, .et al. Discovery and evaluation of inhibitory activity and mechanism of arylcoumarin derivatives on Theileria annulata enolase by in vitro and molecular docking studies, Mol Divers, 2019, Nov 21 PMID: 31754915

Biological Activity

ENOblock (AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.81 mL 84.07 mL 168.15 mL
0.5 mM 3.36 mL 16.81 mL 33.63 mL
1 mM 1.68 mL 8.41 mL 16.81 mL
5 mM 0.34 mL 1.68 mL 3.36 mL

*The above data is based on the productmolecular weight 594.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11840
CAS No. 1177827-73-4
Formula C31H43FN8O3
M. Wt 594.72
Purity >98%
SMILES C1CCC(CC1)CNC2=NC(=NC(=N2)NCC3=CC=C(C=C3)F)NC4=CC=C(C=C4)CC(=O)NCCOCCOCCN
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy ENOblock (AP-III-a4) | ENOblock (AP-III-a4) Supplier | purchase | cost | manufacturer | order | distributor | buy 1177827-73-4| 1177827-73-4 Supplier | purchase 1177827-73-4 | 1177827-73-4 cost | 1177827-73-4 manufacturer | order 1177827-73-4 | 1177827-73-4 distributor
Rewards