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Epothilone D

Catalog No.: A11412

Epothilone D

Epothilone D Chemical Structure

CAS NO. 189453-10-9

Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy.

Availability: In stock

Package Price Qty
1 mg
$50.00
2 mg
$90.00
5 mg
$150.00
10 mg
$240.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Baihong Guo, .et al. Stabilization of microtubules improves cognitive functions and axonal transport of mitochondria in Alzheimer's disease model mice, Neurobiol Aging, 2020, Sep 12;96:223-232 PMID: 33039900

Biological Activity

Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.34 mL 101.69 mL 203.38 mL
0.5 mM 4.07 mL 20.34 mL 40.68 mL
1 mM 2.03 mL 10.17 mL 20.34 mL
5 mM 0.41 mL 2.03 mL 4.07 mL

*The above data is based on the productmolecular weight 491.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11412
CAS No. 189453-10-9
Formula C27H41NO5S
M. Wt 491.68
Purity >98%
Synonyms Desoxyepothilone B, KOS 862
SMILES C[[email protected]]1CCC/C(=C\C[[email protected]](OC(=O)C[[email protected]@H](C(C(=O)[[email protected]@H]([[email protected]]1O)C)(C)C)O)/C(=C/C2=CSC(=N2)C)/C)/C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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