Ixabepilone

Catalog No.: A11449

microtubule inhibitor

Ixabepilone

Ixabepilone Chemical Structure

CAS NO. 219989-84-1

Ixabepilone is an epothilone B analog

Availability: In stock

Package Price Qty
5 mg
$250.00
10 mg
$420.00
25 mg
$840.00
50 mg
$1,450.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Hoque M, .et al. Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors, Pharmacol Res, 2018, Aug;134:166-178 PMID: 29944980
  • APRIL L. RISINGER, .et al. Breast Cancer Cell Lines Exhibit Differential Sensitivities to Microtubule-targeting Drugs Independent of Doubling Time, Anticancer Res, 2015, Nov; 35(11): 5845-5850. PMID: 26504006

Biological Activity

Ixabepilone is an epothilone B analog
Targets
microtubule(tubulin stabilising)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.68 mL 197.36 mL
0.5 mM 3.95 mL 19.74 mL 39.47 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11449
Actions Inhibitor
M. Wt 506.7
Formula C27H42N2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 219989-84-1
Synonyms BMS-24755, Azaepothilone , BMS 247550-1
SMILES C[[email protected]]1CCC[[email protected]@]2([[email protected]@H](O2)C[[email protected]](NC(=O)C[[email protected]@H](C(C(=O)[[email protected]@H]([[email protected]]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C

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