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$0.00 - A Xavier, .et al. hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation Through Sequential GTP Hydrolysis, Cell Rep, 2020, May 19;31(7):107667 PMID: 32433976
Biological Activity
Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
Targets
| Ferroptosis | ||||
| 60 nM(EC50) |
| In vitro (25°C) | DMSO | 45 mg/mL (171.52 mM) | |
| Water | Insoluble | ||
| Ethanol | 45 mg/mL | ||
| In vivo | 2% DMSO+50% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 38.12 mL | 190.59 mL | 381.17 mL |
| 0.5 mM | 7.62 mL | 38.12 mL | 76.23 mL |
| 1 mM | 3.81 mL | 19.06 mL | 38.12 mL |
| 5 mM | 0.76 mL | 3.81 mL | 7.62 mL |
*The above data is based on the productmolecular weight 262.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13247 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 347174-05-4 |
| Formula | C15H22N2O2 |
| M. Wt | 262.35 |
| Purity | >98% |
| Synonyms | Fer1 |
| SMILES | CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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