Biological Activity
Flumatinib mesylate can reduce the expression of C-MYC, HIF-1 a and VEGF in U266 cell line in a time- and dose-dependent manners, so flumatinib mesylate may become a new drug for MM therapy.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 15.18 mL | 75.91 mL | 151.82 mL |
0.5 mM | 3.04 mL | 15.18 mL | 30.36 mL |
1 mM | 1.52 mL | 7.59 mL | 15.18 mL |
5 mM | 0.3 mL | 1.52 mL | 3.04 mL |
*The above data is based on the productmolecular weight 658.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13530 |
---|---|
Actions | Inhibitor |
CAS No. | 895519-91-2 |
Formula | C30H33F3N8O4S |
M. Wt | 658.69 |
Purity | >98% |
SMILES | CC1=C(C=C(C=N1)NC(=O)C2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Regorafenib (BAY 73-4506)
Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. Regorafenib (BAY 73-4506) is an ora…
AC710 Mesylate
AC710 Mesylate is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM/1.0 nM/1.3 nM/1.0 nM for FLT3/KIT/PDGFRα/PDGF…
Pazopanib (GW-786034)
Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit th…
N-Desethyl Sunitinib
N-desethyl sunitinib is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ and KI…
Sunitinib Malate
Sunitinib is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor for the treatment of renal cell carcinoma (RC…
DCC-2618
DCC-2618 is a small molecule inhibitor of c-Kit and PDGFR with IC50s of 6 nM/30 nM/13 nM for c-Kit/PDGFRα/PDGFRβ respectively.
Telatinib (BAY 57-9352)
Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3…
Toceranib (PHA 291639, SU 11654)
Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth facto…
Keywords:buy Flumatinib mesylate | Flumatinib mesylate Supplier | purchase | cost | manufacturer | order | distributor | buy 895519-91-2| 895519-91-2 Supplier | purchase 895519-91-2 | 895519-91-2 cost | 895519-91-2 manufacturer | order 895519-91-2 | 895519-91-2 distributor