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Ganglioside GD3 disodium salt

Catalog No.: A31284
Apoptosis Inducer
Ganglioside GD3 disodium salt is an acidic glycosphingolipid that functions as an apoptosis inducer. It has been shown to inhibit the proliferation of cancer cells, influence the mitochondrial permeability transition pore (mPTP), and activate the caspase family, leading to programmed cell death. This compound is valuable for research applications focused on cancer biology and neurodegenerative diseases.
Ganglioside GD3 disodium salt 497932-19-1 Apoptosis Inducer
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGanglioside GD3 disodium salt is an acidic glycosphingolipid that functions as an apoptosis inducer. It has been shown to inhibit the proliferation of cancer cells, influence the mitochondrial permeability transition pore (mPTP), and activate the caspase family, leading to programmed cell death. This compound is valuable for research applications focused on cancer biology and neurodegenerative diseases.
Product Information
Catalog NumA31284
FormulaC70H123N3Na2O29
Molecular Weight1516.71
CAS Number497932-19-1
SMILESO=C([C@](O[C@@]([C@@H]1NC(C)=O)([H])[C@H](O)[C@@H](CO)O[C@@](O[C@@]([C@@H]2NC(C)=O)([H])[C@H](O)[C@H](O)CO)(C[C@@H]2O)C(O[Na])=O)(C[C@@H]1O)O[C@@H]([C@H]([C@H]3CO)O)[C@H]([C@@H](O3)O[C@@H]([C@@H]([C@H]4O)O)[C@H](O[C@H]4OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC)=O)CO)O)O[Na]
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Apoptosis > Apoptosis Inducers