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Garvicin KS, GakB

Catalog No.: A49271
GarKS Peptide
Garvicin KS, GakB is a 34-amino acid peptide that forms part of the bacteriocin garvicin KS (GarKS) alongside GakA and GakC. This peptide demonstrates significant inhibitory effects on fibroblast viability and proliferation, making it valuable for investigations into cell growth regulation. In addition, Garvicin KS, GakB shows potent antimicrobial activity against methicillin-sensitive Staphylococcus aureus (MSSA), with minimum inhibitory concentration (MIC) values indicating a stronger efficacy compared to GakA and GakC. This makes it a key tool for research in antimicrobial applications and cell proliferation studies.
Garvicin KS, GakB 2098351-25-6 GarKS Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGarvicin KS, GakB is a 34-amino acid peptide that forms part of the bacteriocin garvicin KS (GarKS) alongside GakA and GakC. This peptide demonstrates significant inhibitory effects on fibroblast viability and proliferation, making it valuable for investigations into cell growth regulation. In addition, Garvicin KS, GakB shows potent antimicrobial activity against methicillin-sensitive Staphylococcus aureus (MSSA), with minimum inhibitory concentration (MIC) values indicating a stronger efficacy compared to GakA and GakC. This makes it a key tool for research in antimicrobial applications and cell proliferation studies.
Product Information
Catalog NumA49271
FormulaC145H247N39O37S
Molecular Weight3160.82
CAS Number2098351-25-6
SequenceMet-Gly-Ala-Ile-Ile-Lys-Ala-Gly-Ala-Lys-Ile-Ile-Gly-Lys-Gly-Leu-Leu-Gly-Gly-Ala-Ala-Gly-Gly-Ala-Thr-Tyr-Gly-Gly-Leu-Lys-Lys-Ile-Phe-Gly
Sequence shorteningMGAIIKAGAKIIGKGLLGGAAGGATYGGLKKIFG
SMILES[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCSC)N)=O)=O)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)C)=O)=O)C)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)=O)CCCCN)=O)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)C)=O)C)=O)=O)=O)C)=O)[C@@H](C)O)=O)C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)[C@H](CC)C)=O)CCCCN)=O)CCCCN)=O)CC(C)C)=O)=O)=O
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