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Garvicin KS, GakA

Catalog No.: A49313
GarKS Peptide
Garvicin KS, GakA is a 34-amino acid peptide designed to inhibit the viability and proliferation of fibroblasts. This peptide, part of the garvicin KS bacteriocin family, functions alongside GakB and GakC to enhance antimicrobial efficacy. Notably, Garvicin KS, GakA demonstrates potency against Methicillin-Sensitive Staphylococcus Aureus (MSSA), exhibiting minimum inhibitory concentration (MIC) values that rank GakB as the most effective, followed by GakC and GakA. This peptide's stability and biological activity make it valuable for research in antimicrobial and fibroblast-related applications.
Garvicin KS, GakA 2098351-24-5 GarKS Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGarvicin KS, GakA is a 34-amino acid peptide designed to inhibit the viability and proliferation of fibroblasts. This peptide, part of the garvicin KS bacteriocin family, functions alongside GakB and GakC to enhance antimicrobial efficacy. Notably, Garvicin KS, GakA demonstrates potency against Methicillin-Sensitive Staphylococcus Aureus (MSSA), exhibiting minimum inhibitory concentration (MIC) values that rank GakB as the most effective, followed by GakC and GakA. This peptide's stability and biological activity make it valuable for research in antimicrobial and fibroblast-related applications.
Product Information
Catalog NumA49313
FormulaC161H259N43O39S
Molecular Weight3453.11
CAS Number2098351-24-5
SequenceMet-Gly-Ala-Ile-Ile-Lys-Ala-Gly-Ala-Lys-Ile-Val-Gly-Lys-Gly-Val-Leu-Gly-Gly-Gly-Ala-Ser-Trp-Leu-Gly-Trp-Asn-Val-Gly-Glu-Lys-Ile-Trp-Lys
Sequence shorteningMGAIIKAGAKIVGKGVLGGGASWLGWNVGEKIWK
SMILESC([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC(CNC([C@@H](NC([C@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC([C@@H](NC(CNC(CNC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCSC)N)=O)=O)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)C)=O)=O)C)=O)CCCCN)=O)[C@H](CC)C)=O)C(C)C)=O)=O)CCCCN)=O)=O)[C@H](C)C)=O)CC(C)C)=O)=O)=O)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)=O)CC(N)=O)=O)C(C)C)=O)=O)CCC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O)C=5C=6C(NC5)=CC=CC6
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