Gimatecan

Catalog No.: A12856

topoisomerase I inhibitor

Gimatecan Chemical Structure

CAS NO. 292618-32-7

Gimatecan is an orally bioavailable, semi-synthetic lipophilic analogue of camptothecin, a quinoline alkaloid extracted from the Asian tree Camptotheca acuminate, with potential antineoplastic and antiangiogenic activities.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
25 mg
$1,200.00
50 mg
$2,000.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Gimatecan is an orally bioavailable, semi-synthetic lipophilic analogue of camptothecin, a quinoline alkaloid extracted from the Asian tree Camptotheca acuminate, with potential antineoplastic and antiangiogenic activities.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.35 mL 111.73 mL 223.47 mL
0.5 mM 4.47 mL 22.35 mL 44.69 mL
1 mM 2.23 mL 11.17 mL 22.35 mL
5 mM 0.45 mL 2.23 mL 4.47 mL

*The above data is based on the productmolecular weight 447.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12856
Actions Inhibitor
M. Wt 447.49
Formula C25H25N3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 292618-32-7
Synonyms Lbq707, ST1481, CPT 184
SMILES CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)/C=N/OC(C)(C)C)O

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