GNE-886

Name: GNE-886
Brand: Adooq Bioscience
SKU: A24412
Rating: 5 (288 reviews)

Catalog No.: A24412

CECR2 inhibitor

GNE-886 (Compound 21) is a potent and selective inhibitor of the CECR2 bromodomain (BRD), with an IC₅₀ of 0.016 µM and an EC₅₀ of 370 nM. It also exhibits inhibitory activity against BRD9, with an IC₅₀ of 1.6 µM.

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Grouped product items
Size	Price	Stock
5mg	$405.00	In stock
10mg	$698.00	In stock
50mg	$2,070.00	In stock
100mg	$4,050.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	GNE-886 (Compound 21) is a potent and selective inhibitor of the CECR2 bromodomain (BRD), with an IC₅₀ of 0.016 µM and an EC₅₀ of 370 nM. It also exhibits inhibitory activity against BRD9, with an IC₅₀ of 1.6 µM.

Product Information

Catalog Num	A24412
Formula	C28H30N6O3
Molecular Weight	498.58
CAS Number	2101957-05-3
SMILES	O=C(C1=CN(CC=C)C(C2=C1C=CN2)=O)N(C3CCN(C4=NC=NC(C5=CC=CC(OC)=C5)=C4)CC3)C
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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