TP-238 hydrochloride is a potent and selective dual probe for CECR2 and BPTF, with IC₅₀ values of 30 nM and 350 nM, respectively. It also inhibits BRD9 with a pIC₅₀ of 5.9 and shows minimal activity against a panel of 338 other kinases.
TP-238 hydrochloride is a potent and selective dual probe for CECR2 and BPTF, with IC₅₀ values of 30 nM and 350 nM, respectively. It also inhibits BRD9 with a pIC₅₀ of 5.9 and shows minimal activity against a panel of 338 other kinases.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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