GNF-7
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively. | ||
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Targets |
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Catalog Num | A15887 |
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Formula | C28H24F3N7O2 |
Molecular Weight | 547.53 |
CAS Number | 839706-07-9 |
SMILES | O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC=C(C)N=C4)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5 |
Synonyms | GNF7, GNF 7 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 17 mg/mL (31.04 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.26 mL | 91.32 mL | 182.64 mL |
0.5 mM | 3.65 mL | 18.26 mL | 36.53 mL |
1 mM | 1.83 mL | 9.13 mL | 18.26 mL |
5 mM | 0.37 mL | 1.83 mL | 3.65 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2