GSK761

Name: GSK761
Brand: Adooq Bioscience
SKU: A24393
Rating: 5 (288 reviews)

Catalog No.: A24393

SP140 Inhibitor

GSK761 is a selective inhibitor of speckled 140 kDa (SP140) protein, with an IC50 of 77.79 nM. It suppresses monocyte-to-inflammatory macrophage differentiation and lipopolysaccharide (LPS)-induced inflammatory activation. Additionally, GSK761 promotes the production of CD206+ regulatory macrophages by inhibiting SP140.

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Grouped product items
Size	Price	Stock
5mg	$315.00	In stock
10mg	$543.00	In stock
50mg	$1,610.00	In stock
100mg	$3,150.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	GSK761 is a selective inhibitor of speckled 140 kDa (SP140) protein, with an IC50 of 77.79 nM. It suppresses monocyte-to-inflammatory macrophage differentiation and lipopolysaccharide (LPS)-induced inflammatory activation. Additionally, GSK761 promotes the production of CD206+ regulatory macrophages by inhibiting SP140.

Product Information

Catalog Num	A24393
Formula	C40H46N4O4
Molecular Weight	646.82
CAS Number	nan
SMILES	CN1C2=CC=C(C=C2N=C1C3=CC=C(C=C3)C(NC4=CC(CCOC(C)(C)C)=CC=C4)=O)C(NC5=CC(CCOC(C)(C)C)=CC=C5)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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